Systematic review to identify and appraise patient-reported outcome measures on treatment satisfaction in acne.

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After dermatitis, acne is the second skin disease most contributing to the burden of skin diseases worldwide. Recently, seven core outcome domains have been identified that together form an Acne Core Outcome Set (ACORN project). One of these was satisfaction with acne treatment.Our aim was to identify studies that described the development of patient-reported outcome measures (PROMS), evaluated one or more measurement properties of a PROM, or evaluated the interpretability of a PROM in patients with acne regarding treatment satisfaction.The COSMIN search strategy for identifying PROMS on acne treatment satisfaction was used. We searched Pubmed, MEDLINE, Embase, LILACS, Web of Science, Cochrane Library, Emcare, PsychINFO and Academic Search premier (June 2020). Study selection, data extraction, and assessment of methodological quality according to COSMIN guidance were carried out independently by two authors.Only one study could be included, describing the development of a treatment satisfaction measure in patients with acne. The development was assessed as inadequate, and data on measurement properties were lacking. Additionally, we found 188 studies reporting treatment satisfaction solely as an outcome, using a wide variety of methods, none of them standardised nor validated.We could not find a PROM on treatment satisfaction to recommend for a core outcome set in acne. There is an unmet need for a PROM measuring treatment satisfaction in acne that is robustly developed, designed and validated.


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