Real-world experience on off-label use of imiquimod 5% as an adjuvant therapy after surgery or as a monotherapy for lentigo maligna.

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Because of the tendency of lentigo maligna (LM) for subclinical extension, staged excisions with margin control achieve lower recurrence rates than conventional wide local excision (0-9.5% vs 8-20%). However, these surgical techniques are limited by their requirement in time, costs and training.


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Authors: A Lallas, E Moscarella, H Kittler, C Longo, L Thomas, I Zalaudek, A Kyrgidis, S M Manoli, N di Meo, C Papageorgiou, Z Apalla, G Argenziano

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