Not all melanomas are created equal: A review and call for more research into nodular melanoma.

Like Comment
Among the histogenic subtypes of melanoma, nodular melanoma (NM) is the major contributor for thicker and fatal melanomas and it has been associated with melanoma-specific death in thin tumours highlighting an important subgroup of 'aggressive thin' melanomas. This review provides a synthesis of the distinct characteristics of NM, with respect to epidemiology and risk factors, clinical presentation, histopathology, molecular and dermoscopic aspects, and screening practices. The real challenges are to find better biomarkers of aggressiveness and to know whether the control of such aggressive melanoma can be influenced by targeted interventions such as early detection, drug interventions and preventive strategies.


View the full article @ The British journal of dermatology


Get PDF with LibKey
Authors: C Dessinioti, A C Geller, D C Whiteman, C Garbe, J J Grob, J W Kelly, R A Scolyer, R V Rawson, A Lallas, G Pellacani, A J Stratigos

ClinOwl

The wider, wiser view for healthcare professionals. ClinOwl signposts the latest clinical content from over 100 leading medical journals.
6577 Contributions
2 Followers
0 Following