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According to NICE draft guidance, clinical trial evidence suggests romosozumab followed by alendronic acid is more effective at reducing the risk of fractures than alendronic acid alone. But there is uncertainty because the population in the clinical trial is different to the proposed population.
Interventional procedures guidance: percutaneous implantation of pulmonary artery pressure sensors for monitoring treatment of chronic heart failure
According to NICE, evidence on the safety and efficacy of the procedure is adequate to support its use provided that standard arrangements are in place for clinical governance, consent and audit.