Cigarette smoking and risk of herpes zoster: A population-based cohort study in Taiwan.

The effects of cigarette smoking on the risk of herpes zoster (HZ) remain unclear. This study aimed to examine the association between cigarette smoking and HZ. Participants were collected from four rounds (2001, 2005, 2009, and 2013) of the Taiwan National Health Interview Survey. Incident cases of HZ were identified from the National Health Insurance database. Of the 57,641 participants, 3,346 developed HZ during the observation period. After controlling for confounders, current smokers had a lower risk of incident HZ than never smokers (adjusted hazard ratio: 0.69; 95% confidence interval: 0.62-0.77). There was a trend toward a decreased risk of HZ with increasing numbers of cigarettes per day, years of smoking, and cumulative pack-years of smoking among current smokers (Ptrend

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Authors: Y-X Dai, F-Y Yeh, Y-J Shen, Y-H Tai, N Huang, Y-T Chang, T-J Chen, C-P Li, C-Y Wu