Chloracne: a case series on cutaneous expression of CYP1A1 as diagnostic biomarker.

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The term dioxin is commonly used to describe a group of ubiquitous environmental contaminants: polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans (PCDD/Fs, 209 different compounds). The best studied compound among the group in relation to its higher toxicity is 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD). Polychlorinated biphenyls (PCBs) are a group of environmental compounds containing certain substances known as "dioxin-like PCBs (dl-PCBs)" with a similar mechanism of action to dioxins.


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Authors: M A Chessa, M La Placa, A Patrizi, A Virdi, M Cosimo, F Giorgio, F Filippi, J-H Saurat, O Sorg, F Fontao, G Kaya, I Neri

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