How to treat melanoma?

This visual summary, based on NICE guidance, outlines the different management options for the different stages of melanoma.

Interim treatment regimens during the COVID-19 pandemic1

NHS England has published interim treatment changes1 to allow for greater flexibility in the management of cancer during COVID-19 pandemic to ensure clinicians have additional treatment options through this time.

It give the following recommendations regarding the management of melanoma: 

  • Give oral therapy as first-line treatment for BRAF positive patients in preference to immunotherapy to reduce admission for intravenous therapy.
  • Stop immunotherapy doublet (ipilimumab and nivolumab) and switch to single agent nivolumab or pembrolizumab to reduce toxicity.


  1. NHS England interim treatment changes during the COVID-19 pandemic. Last updated 12 August 2020.

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