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Cancer care is ‘ageist’ claims expert

Elderly patients are ‘undertreated’ worldwide

Jo Carlowe

Tuesday, 11 March 2014

Older people globally are being denied proper access to cancer care.

According to an editorial by Queen's University Belfast academic, Professor Mark Lawler of the Centre for Cancer Research and Cell Biology, elderly patients around the world are being “undertreated”.

Writing in the BMJ, Professor Lawler spoke of a “survival gap” between older and younger patients.

"We need a fundamental change in cancer policy for the elderly patient. Our current practices are essentially ageist, as we are making judgments based on how old the patient is rather than on their capacity to be entered into clinical trials or to receive potentially curative therapy,” he said.

He added: “It is disappointing that we see different principles being applied for older patients when compared to younger patients, with these differences leading to poorer outcomes in the elderly patient population."

Professor Lawler's findings are published in an editorial in the BMJ entitled, 'Ageism In Cancer Care: We Need to Change The Mindset'. It states the need to redress the disparities in the policy on cancer for older patients, citing a recent position paper from the European Organisation for Research and Treatment of Cancer, the Alliance for Clinical Trials in Oncology and the International Society of Geriatric Oncology recommending that clinical trials should be without an upper age limit.

A high proportion of older women with a certain form of breast cancer ('triple negative') receive less chemotherapy than their younger counterparts - despite evidence of the treatment's efficacy in this patient cohort, the authors claim.

They also point out that more than 70% of deaths caused by prostate cancer occur in men aged over 75 years, who usually have more aggressive disease. Few older patients, however, receive treatment for localised prostate cancer, and in most cases they are denied access to chemotherapy for advanced disease, they add.

"Colorectal cancer is another disease of older people, yet the evidence again suggests that optimal treatment is not being provided to this patient cohort," Professor Lawler continues.

The paper sets its argument within the context of an ageing society – both locally and globally. Estimates for the UK suggest that 76% of cancers in men and 70% of cancers in women will occur in the over-65 population by 2030.

The International Cancer Benchmarking Partnership – a collaboration that compares clinical outcomes between Australia, Canada, Denmark, England, Northern Ireland, Norway, Sweden and Wales – has indicated decreased survival for patients older than 65 years. A EUROCARE 5 study confirmed this trend, suggesting that the survival gap was widening between older and younger patients in Europe.

The evidence provided highlights the “urgent need” for a “geriacentric” strategy that maximises clinical trial activity in older patients, makes existing treatments more available and develops new approaches that are well tolerated in older people, states the paper.

Professor Lawler concludes: "Such a strategy will also have to ensure that the principle of early diagnosis (underpinning more effective and less aggressive treatment) is applied in older patients as well as in their younger counterparts. Only then can we truly deliver a comprehensive cancer service to the elderly population in our society.”

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