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Clinical articles

Our clinical articles provide comprehensive overviews of a large range of clinical topics and include helpful key learning points. Log your learning in your PDP tracker to claim CME credits.

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NICE recommends in final draft guidance: ribociclib with fulvestrant on CDF for advanced breast cancer, risankizumab for plaque psoriasis, dapagliflozin with insulin for type 1 diabetes
ELISA tests for therapeutic monitoring of TNF-alpha inhibitors not recommended by NICE for routine adoption in rheumatoid arthritis; SMC accepts palbocicli for advanced or metastatic breast cancer; MHRA issues drug alert for Phenobarbital Sodium 30mg/ml Injection
A review the aetiology, diagnosis and management of immune thrombocytopenic purpura (immune thrombocytopenia, ITP) in children and adults
A clinical review of the third most common clinical endocrine disorder after diabetes and thyroid disease and for which surgery is the only curative therapy
Dacomitinib now recommended for non-small-cell lung cancer in NICE draft guidance; CHMP recommends Giapreza for refractory hypotension; MHRA issues medical device alert for IntelliVue MX40 patient-worn monitors
An overview of pre-eclampsia and its management with reference to the latest NICE guidance
An overview of multiple myeloma, a progressive malignant disease of plasma cells
Lenalidomide plus dexamethasone recommended as first- and second-line treatment for multiple myeloma in NICE final guidance; AWMSG recommends rufinamide as adjunctive therapy for seizures associated with Lennox-Gastaut syndrome (restricted)
MHRA issues several drug safety updates, including on direct-acting oral anticoagulants, and GLP-1 receptor agonists; NICE now recommends blinatumomab for acute lymphoblastic leukaemia
NICE recommends ocrelizumab for primary progressive multiple sclerosis in final guidance; SMC accepts nivolumab in combination with ipilimumab for advanced renal cell carcinoma
NICE recommends ertugliflozin in triple therapy for type 2 diabetes; recommendations published on the use of paclitaxel drug-coated balloons and drug-eluting stents
A overview of the third most common cancer in the UK, covering epidemiology, presentation, investigation, staging, management and prognosis
NICE recommends letermovir to prevent cytomegalovirus disease in draft guidance; EMA gives positive opinion for Cufence for Wilson’s disease; NHS England announces more than 50,000 people use Personal Health Budgets
MHRA issues drug safety updates on magnesium sulfate, tofacitinib and alemtuzumab (Lemtrada); primary hyperparathyroidism NICE guideline published; EMA announces withdrawal of marketing authorisations for fenspiride medicines
A review of the definition, aetiology and assessment of delirium, including the role of good history taking, screening tools, examination and investigations
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