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Clinical articles

Our clinical articles provide comprehensive overviews of a large range of clinical topics and include helpful key learning points. Log your learning in your PDP tracker to claim CME credits.

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Tisagenlecleucel recommended through CDF for relapsed or refractory diffuse large b-cell lymphoma after two or more systemic therapies in final NICE guidance; SIGN guideline on risk reduction and management of delirium published
Diabetic retinopathy is a leading cause of visual impairment. This article provides an overview of the clinical features and management of this common condition
NICE updated draft hypertension guidance reduces threshold for CVD risk; benralizumab recommended for severe eosinophilic asthma in final NICE guidance; pharmacies now able to dispense controlled drugs via EPS
This clinical article gives a broad overview of alcohol abuse, covering epidemiology and impact, identification and assessment, management and links to patient resources
Although acute liver failure is a rare presentation in general practice, it is a medical emergency and has a high mortality
Early diagnosis of chronic liver disease is essential to address the underlying cause and so reduce the risk of complications and improve prognosis
Encorafenib with binimetinib for unresectable or metastatic melanoma recommended in NICE final guidance; medical device alert issued for various GE Healthcare parameter patient monitors
Brigatinib now recommended for advanced lung cancer in NICE final draft guidance; drug safety update issued by MHRA for SGLT2 inhibitors due to reports of Fournier’s gangrene
Perjeta now recommended for new breast cancer indication in NICE final draft guidance but Tecentriq not recommended for lung cancer in draft guidance; Class 2 medicines recall on some irbesartan tablets
First oral add-on tablet to insulin treatment for certain patients with type 1 diabetes recommended; antimicrobial prescribing guideline for acute cough published
A review of the presentation, investigation and management of this common condition which can be caused by a variety of pathologies
CAR T-cell therapy now recommended within CDF for lymphoma; UrgoStart recommended for treating diabetic foot and leg ulcers; MHRA issues several recalls; positive EAMS scientific opinion for dupilumab; Carbagen shortage
Acute angle closure glaucoma causes severe eye pain and visual disturbance. Emergency treatment is required to prevent permanent loss of vision.
Primary open angle glaucoma is the commonest cause of glaucoma. The prevalence increases with age and is often unnoticed until there is irreversible damage to the optic nerve.
NICE recommends digital CBT for children and young people with mild depression in draft guidance; FSRH publishes updated guidance on combined hormonal contraceptives; SIGN publishes guideline on diagnosing foetal alcohol spectrum disorder
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