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CBT for the treatment of resistant depression

Portfolio politics

Louise Newson

Monday, 10 December 2012

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LB_Blog_Depression_10_12_2012.jpgIt is now well accepted that patients with mild to moderate depression respond well to cognitive behavioural therapy (CBT) and this is actually one of the recommended treatments. CBT is a form of talking psychotherapy to help people with depression change the way they think to improve how they feel and alter their behaviour. In fact up to two-thirds of people with depression do not actually respond to anti-depressants.

A recent study in the Lancet has demonstrated that CBT can reduce symptoms of depression in people who fail to respond to drug treatment. After six months of receiving CBT, 46% of patients who had received CBT reported at least a 50% reduction in their symptoms. The improvements had been maintained for a period of 12 months, it added. CBT was used in addition to medication for some patients. This is the first randomised controlled study to show that CBT as an adjunct to usual care that includes antidepressants is an effective treatment

Patients with severe and chronic depression were, however, less likely to respond to CBT.

These results add to a wealth of evidence demonstrating the benefits of CBT for managing depression. Depression is very common and its incidence is increasing. However, it is a shame that there still is a huge variation in the types of treatment people with depression receive between different areas in the UK.

In my practice, we seldom refer patients with depression for CBT as the waiting list is in excess of six months. Perhaps the result of this study will help to reduce this wait in the future.

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Louise Newson

Louise is a part-time GP in Solihull, as well as a writer for numerous medical publications, including She is an Editor and Reviewer for e-learning courses for the RCGP. She is an Editor for Geriatric Medicine journal and the British Journal of Family Medicine. Louise has contributed to various healthcare articles in many different newspapers and magazines and is the spokesperson for The Information Standard. She has also done television and radio work. Louise is a medical consultant for Maverick TV and has participated regularly in ‘Embarrassing Bodies Live from the Clinic’. Louise has three young children and is married to a consultant urological surgeon. Although her spare time is limited she enjoys practising ashtanga yoga regularly and loves road cycling – she has raised over £2K for a local charity, Molly Olly Wishes by competing in a 120km cycle ride!
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